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Table 3 The cytokine profile in different groups

From: Association between cytokine profiles and lung injury in COVID-19 pneumonia

  Overall (n = 106) COVID-19 without pneumonia/Mild (n = 12) COVID-19 with pneumonia(n = 94) p –values Moderate (n = 69) Severe (n = 25) p –values
IL-1β, pg/mL 5.00 (5.00–5.00) 5.00 (5.00–5.00) 5.00 (5.00–5.00) 0.726 5.00 (5.00–5.00) 5.00 (5.00–5.00) 0.829
IL-2R, U/mL 424.50 (268.75–692.75) 260.00 (229.25–358.50) 463.50 (281.50–716.75) 0.002 381.00 (266.00–631.00) 725.00 (471.00–968.50) < 0.001
IL-6, pg/mL 3.48 (1.63–11.39) 1.85 (1.50–2.74) 3.86 (1.79–13.60) 0.016 2.90 (1.59–7.29) 17.05 (3.95–120.00) < 0.001
IL-8, pg/mL 9.30 (6.25–12.48) 7.05 (6.15–11.18) 9.35 (6.45–12.95) 0.223 8.90 (5.80–12.05) 11.50 (9.05–18.00) 0.036
IL-10, pg/mL 5.00 (5.00–5.00) 5.00 (5.00–5.53) 5.00 (5.00–5.00) 0.849 5.00 (5.00–5.00) 5.00 (5.00–6.44) 0.198
TNF-α, pg/mL 7.60 (6.10–9.70) 6.35 (5.43–7.15) 7.95 (6.28–9.95) 0.016 7.50 (6.10–9.70) 8.70 (7.40–11.85) 0.007
  1. Abbreviation: IL interleukin, TNF tumor necrosis factor, COVID-19 coronavirus disease 2019