Table 3 The cytokine profile in different groups
From: Association between cytokine profiles and lung injury in COVID-19 pneumonia
Overall (n = 106) | COVID-19 without pneumonia/Mild (n = 12) | COVID-19 with pneumonia(n = 94) | p –values | Moderate (n = 69) | Severe (n = 25) | p –values | |
|---|---|---|---|---|---|---|---|
IL-1β, pg/mL | 5.00 (5.00–5.00) | 5.00 (5.00–5.00) | 5.00 (5.00–5.00) | 0.726 | 5.00 (5.00–5.00) | 5.00 (5.00–5.00) | 0.829 |
IL-2R, U/mL | 424.50 (268.75–692.75) | 260.00 (229.25–358.50) | 463.50 (281.50–716.75) | 0.002 | 381.00 (266.00–631.00) | 725.00 (471.00–968.50) | < 0.001 |
IL-6, pg/mL | 3.48 (1.63–11.39) | 1.85 (1.50–2.74) | 3.86 (1.79–13.60) | 0.016 | 2.90 (1.59–7.29) | 17.05 (3.95–120.00) | < 0.001 |
IL-8, pg/mL | 9.30 (6.25–12.48) | 7.05 (6.15–11.18) | 9.35 (6.45–12.95) | 0.223 | 8.90 (5.80–12.05) | 11.50 (9.05–18.00) | 0.036 |
IL-10, pg/mL | 5.00 (5.00–5.00) | 5.00 (5.00–5.53) | 5.00 (5.00–5.00) | 0.849 | 5.00 (5.00–5.00) | 5.00 (5.00–6.44) | 0.198 |
TNF-α, pg/mL | 7.60 (6.10–9.70) | 6.35 (5.43–7.15) | 7.95 (6.28–9.95) | 0.016 | 7.50 (6.10–9.70) | 8.70 (7.40–11.85) | 0.007 |