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Table 2 The laboratory data in different groups

From: Association between cytokine profiles and lung injury in COVID-19 pneumonia

  Overall (n = 106) COVID-19 without pneumonia/Mild (n = 12) COVID-19 with pneumonia(n = 94) p –values Moderate (n = 69) Severe (n = 25) p –values
White-cell count, ×109/L 6.12 ± 2.29 5.80 ± 1.46 6.16 ± 2.38 0.618 6.03 ± 2.17 6.49 ± 2.92 0.615
Neutrophil count,× 109/L 3.98 ± 2.14 3.44 ± 1.16 4.05 ± 2.23 0.357 3.77 ± 2.02 4.81 ± 2.64 0.075
Lymphocyte count, ×109/L 1.50 ± 0.68 1.78 ± 0.54 1.46 ± 0.69 0.128 1.59 ± 0.67 1.12 ± 0.66 0.003
Hemoglobin, g/L 128.16 ± 21.07 132.17 ± 13.70 127.65 ± 21.83 0.487 130.71 ± 21.13 119.20 ± 21.91 0.049
PLT, ×109/L 228.16 ± 91.20 215.08 ± 59.31 229.83 ± 94.60 0.600 234.59 ± 81.12 216.68 ± 125.64 0.615
ALT, U/L 24.50 (13.75–40.25) 24.50 (10.75–39.75) 24.50 (14.00–41.75) 0.654 25.00 (13.00–40.50) 24.00 (14.00–42.50) 0.883
AST, U/L 22.50 (15.00–32.25) 21.50 (15.50–27.50) 23.00 (15.25–35.25) 0.460 20.00 (14.50–52.00) 24.00 (15.50–46.00) 0.313
CK,U/L (n = 105) 76.09 ± 40.77 84.58 ± 34.67 74.99 ± 41.53 0.227 71.31 ± 36.51 85.00 ± 52.41 0.268
CK-MB, ng/mL (n = 105) 1.95 ± 4.49 0.67 ± 0.33 2.12 ± 4.75 0.083 1.08 ± 1.78 4.95 ± 8.14 < 0.001
LDH, U/L 193.00 (159.75–241.25) 180.00 (157.75–200.25) 196.50 (160.75–260.75) 0.214 190.00 (155.00–235.00) 239.00 (182.00–672.80) 0.007
APTT, s 37.65 (35.55–40.70) 36.90 (35.33–39.53) 37.90 (35.60–41.20) 0.440 38.30 (35.65–41.20) 36.50 (32.25–40.50) 0.085
PT, s 13.40 (12.80–13.93) 13.20 (12.90–13.68) 13.40 (12.83–14.00) 0.321 13.40 (12.90–14.00) 13.20 (11.85–14.30) 0.281
d-dimer, μg/mL 0.06 (0.05–0.08) 0.22 (0.22–0.22) 0.37 (0.22–0.81) 0.009 0.28 (0.22–0.64) 0.70 (0.32–1.50) < 0.001
FIB, g/L 3.96 ± 1.60 3.05 ± 0.54 4.07 ± 1.65 < 0.001 3.78 ± 1.47 4.89 ± 1.87 0.001
Hs-CRP, mg/L (n = 98) 2.30 (0.68–8.40) 0.90 (0.33–1.83)(86) 2.45 (0.98–11.85) 0.008 2.25 (0.60–8.75) 3.95 (2.30–47.80) 0.002
PCT, ng/ml (n = 97) 0.06 (0.05–0.08 0.06 (0.05–0.07) 0.07 (0.05–0.09) 0.121 0.06 (0.05–0.08)(62) 0.08 (0.06–0.30) 0.001
  1. Abbreviation: IL interleukin, TNF tumor necrosis factor, Hs-CRP high-sensitivity C-reactive protein, CT computed tomography, PCT procalcitonin, COVID-19 coronavirus disease 2019, PLT platelet, ALT alanine aminotransferase, AST aspartate aminotransferase, CK creatine kinase, LDH lactic dehydrogenase, APTT activated partial thromboplastin time, PT prothrombin time, FIB fibrinogen