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Table 6 Test characteristics of cut-off values of CIRP for mortality in patients hospitalized with CAP (n = 404)

From: Cold-inducible RNA-binding protein might determine the severity and the presences of major/minor criteria for severe community-acquired pneumonia and best predicted mortality

CIRP (ng/mL)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Youden’s index

≥ 0.75

100

0

10.9

0

0

≥ 1.75

95.5

30.8

14.4

98.2

0.26

≥ 2.25

95.5

43.1

17.0

98.7

0.39

≥ 2.75

93.2

56.9

20.9

98.6

0.50

≥ 3.50

61.4

88.9

40.3

95.0

0.50

≥ 4.50

36.4

96.9

59.3

92.6

0.33

  1. CIRP Cold-inducible RNA-binding protein, CAP Community-acquired pneumonia, PPV Positive predictive value, NPV Negative predictive value