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Fig. 3 | Respiratory Research

Fig. 3

From: SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis

Fig. 3

Single cell RNA-sequencing analysis of ACE2, TMPRSS2. ADAM17, TIMP3, AGT, TGFB1, CTGF. VEGFA and FN1 mRNAs in human airways and lungs. a Single cells were isolated from human bronchial biopsy (n = 4) and subjected to RNA-sequencing. Cells were clustered using a graph-based shared nearest neighbour clustering approach and visualised using a t-distributed Stochastic Neighbor Embedding (tSNE) plot from UCSC cell browser. b mRNA expression of ACE2, TMPRSS2. ADAM17, TIMP3, TGFB1, CTGF, VEGFA and FN1 in different cells from human airways. c Single cells were isolated from human lungs (n = 12) and the cells were clustered using tSNE plot from UCSC cell browser. d mRNA expression of ACE2, TMPRSS2. ADAM17, TIMP3, TGFB1, CTGF, VEGFA and FN1in different cells from human lungs

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Respiratory Research

ISSN: 1465-993X

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