Table 5 Bronchodilator response in FEV1 at asthma diagnosis by age groups in COREA cohort
From: Relationship between age and bronchodilator response at diagnosis in adult-onset asthma
Age at asthma diagnosis < 40 years n = 245 | Age at asthma diagnosis 40–59.9 years n = 316 | Age at asthma diagnosis ≥ 60 years n = 224 | p-value | |
|---|---|---|---|---|
FEV1 BDR mL | 153 ± 268 | 139 ± 192 | 101 ± 175 a | < 0.001 |
FEV1 BDR % | 7.9 ± 14.1 | 8.4 ± 12.8 | 8.6 ± 13.9 | 0.631 |
Patients with > 400 mL BDR in FEV1 | 37 (15.1%) | 20 (6.3%) a | 9 (4.0%) a | < 0.001 |
Patients with ≥200 mL BDR in FEV1 | 95 (38.8%) | 104 (32.9%) | 49 (21.9%) a,b | < 0.001 |
Patients with ≥12% BDR in FEV1 | 58 (23.7%) | 94 (29.8%) | 73 (32.6%) | 0.088 |
Patients with ≥200 mL and 12% BDR in FEV1 | 55 (22.5%) | 79 (25.0%) | 46 (20.5%) | 0.467 |