Table 1 Baseline clinical characteristics of the 245 patients included from the SAAS cohort

Age, years

29.2 ± 7.0

50.6 ± 5.3

68.0 ± 5.3

NA

Gender male

33 (39.8%)

48 (41.7%)

22 (46.8%)

0.733

BMI kg·m^− 2

25.5 (23.1–30.0)

27.1 (24.3–30.1)

28.7 (26.4–31.6) ^a

0.006

Smoking status

0.003

 Never smokers

46 (55.4%)

49 (42.6%)

23 (48.9%)

 Ex-smokers

14 (16.9%)

43 (37.4%) ^a

20 (42.6%) ^a

 Current smokers

23 (27.7%)

23 (20.0%)

4 (8.5%) ^a

Pack-years (of ex/current smokers)

5 (3–18)

15 (7–20) ^a

24 (10–38) ^a,b

< 0.001

Steroid medication in use

4 (4.9%)

10 (8.7%)

4 (8.5%)

0.582

B-eosinophils ×10⁹/L

0.30 (0.19–0.46)

0.22 (0.16–0.40)

0.24 (0.18–0.45)

0.341

IgE kU/L ^c

98 (38–237)

75 (28–145)

71 (21–138)

0.108

Skin prick positive

41 (54.7%)

30 (29.1%) ^a

6 (14.6%) ^a

< 0.001