Table 2 Exacerbation Data and Clinical Outcomes in Patients with CPFE and IPF
From: Acute exacerbations of COPD versus IPF in patients with combined pulmonary fibrosis and emphysema
CPFE (n = 85) | IPF (n = 112) | P value | ||
|---|---|---|---|---|
Acute Exacerbation preceding lung transplantation | 22/85 (25.8%) | 45/112 (40.18%) | 0.023 | |
AE-COPD | AE-IPF | * < 0.01 | ||
10/85 (11.7%) | 12/85 (14.1%) | |||
Rate of exacerbation per person-year | 0.284 | 0.273 | 0.85 | |
0.115 | 0.219 | *0.13 | ||
**0.053 | ||||
Need for invasive mechanical ventilation | 10/22 (45%) | 20/45 (44.44%) | 0.8 | |
2/22 (9%) | 8/22 (36%) | * < 0.01 | ||
Need for invasive mechanical ventilation and ECMO | 3/22 (13.6%) | 17/45 (37.8%) | 0.043 | |
0/22 (0%) | 3/22 (13.6%) | * < 0.01 | ||
Exacerbation-related mortality | 5/22 (22.7%) | 14/45 (31.1%) | 0.47 | |