Table 1 Baseline Characteristics
From: Acute exacerbations of COPD versus IPF in patients with combined pulmonary fibrosis and emphysema
CPFE (n = 85) | IPF (n = 112) | P value | |
|---|---|---|---|
Age (year) | 66.4 (6.7) | 66.7 (6.2) | 0.72 |
Gender (F) | 13 (15.29%) | 31 (27.68%) | 0.039 |
Ethnicity | 0.225 | ||
Caucasian | 75 (88%) | 98 (87.5%) | |
Hispanic | 1 (1.2%) | 6 (5.36%) | |
African American | 9 (10.6% | 8 (7.14%) | |
Prior History of Smoking | 85 (100%) | 66 (58.9%) | < 0.01 |
Pack-years | 42.47 (20.2) | 22.2 (11) | < 0.01 |
BMI (kg/m2) | 29.4 (4.5) | 27.9 (4.4) | 0.02 |
FVC (L) | 2.73 (0.79) | 1.75 (0.55) | < 0.01 |
FVC % | 69.2 (18.1) | 45.6 (11.7) | < 0.01 |
FEV1 (L) | 2.04 (0.6) | 1.48 (0.46) | < 0.01 |
FEV1% | 69.6 (22.5) | 51.8 (13.8) | < 0.01 |
FEV1/FVC | 74.0 (12.84) | 84.54 (7.27) | < 0.01 |
TLC (L) | 4.17 (1.2) | 2.89 (0.7) | < 0.01 |
TLC % | 66.1 (16.5) | 47.17 (8.6) | < 0.01 |
RV (L) | 1.4 (0.61) | 0.93 (0.32) | < 0.01 |
RV (%) | 59.24 (29.6) | 41.63 (13.4) | < 0.01 |
RV/TLC | 32.8 (7.3) | 32.1 (9.0) | 0.61 |
DLCO % | 21.5 (8.2) | 27.1 (11.5) | < 0.01 |
DLCO/VA % | 39.34 (14.4) | 57.14 (17.6) | < 0.01 |
PaO2 (mmHg) | 55.9 (12.9) | 54.78 (11.6) | 0.53 |
PCO2 (mmHg) | 37.23 (6.0) | 39.81 (5.9) | 0.04 |
O2 at rest (LPM) | 3.14 (2.5) | 3.23 (2.5) | 0.79 |
O2 on exertion (LPM) | 13.0 (3.6) | 10.3 (3.9) | 0.033 |
6-MWTD (meters) | 260.2 (86.7) | 260 (82) | 0.98 |
LVEF (%) | 61.5 (6.6) | 62.2 (6.7) | 0.47 |
Pulmonary HTN (%) | 38 (44.7%) | 33 (29.5%) | 0.027 |
mPAP (mmHg) | 28.43 (10.8) | 23.5 (9.1) | < 0.01 |
PCWP (mmHg) | 9.84 (5.5) | 7.95 (4.8) | 0.011 |
PVR (Wood units) | 4.3 (3.2) | 3.37 (2.1) | 0.016 |