Fig. 2From: Composite endpoints in COPD: clinically important deterioration in the UPLIFT trialKaplan–Meier estimates of time to first subsequent SGRQ deterioration or first subsequent FEV1 deterioration. Kaplan–Meier estimates of median time from FEV1 decline ≥100 mL to SGRQ score deterioration ≥4 units, and median time from SGRQ score deterioration ≥4 units to FEV1 decline ≥100 mL in the overall population. CI: confidence interval; FEV1: forced expiratory volume in 1 s; NE: not evaluable; SGRQ: St. George’s Respiratory QuestionnaireBack to article page