Fig. 1
From: Composite endpoints in COPD: clinically important deterioration in the UPLIFT trial
Kaplan–Meier estimates for the time to CID in the overall population and GOLD subgroups. Kaplan–Meier estimates of time to first event, two of three events, or three of three events of the components of the composite endpoint (trough FEV1 decline ≥100 mL, SGRQ score deterioration ≥4 units, or moderate/severe exacerbation) in (a) the overall population, (b) GOLD 2 patients, (c) GOLD 3 patients, and (d) GOLD 4 patients. - indicates either that this value could not be assessed (median was not estimable) or is not applicable (HR only displayed for time to event analysis). CI: confidence interval; FEV1: forced expiratory volume in 1 s; GOLD: Global Initiative for Chronic Obstructive Lung Disease; HR: hazard ratio; SGRQ: St. George’s Respiratory Questionnaire