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Table 1 Basic characteristics of the study population, comparing individuals with COPD and normal lung function (NLF)

From: Cardiac biomarkers of prognostic importance in chronic obstructive pulmonary disease

CategoryVariablesCOPD (n = 601)NLF (n = 755)p
AgeAge, mean (SD)67.0 (10.6)64.5 (11.3)< 0.001
SexWomen253 (42.1)361 (47.8)0.036
Smoking habits   < 0.001
 Never smoker153 (25.5)354 (46.9) 
 Ex-smoker250 (41.6)303 (40.1) 
 Current smoker198 (32.9)98 (13.0) 
BMI groups   0.025
 BMI < 2020 (3.3)12 (1.6) 
 BMI 20–24.9206 (34.3)238 (31.5) 
 BMI 25–29.9279 (46.4)347 (46.0) 
 BMI ≥3096 (16.0)158 (20.9) 
Oxygen saturationSaturation percent, mean (SD)96.2 (2.2)97.1 (1.3)< 0.001
 Hypoxemia (< 92%)8 (1.3)0 (0)0.001
ExacerbationsHospital admission last 12 months111 (1.8)11 (1.5)0.589
ComorbiditiesDiabetes mellitus54 (9.0)64 (8.5)0.742
 Angina pectoris76 (12.2)80 (10.6)0.240
 Myocardial infarction35 (5.8)19 (2.5)0.002
 CABG and/or PCI23 (3.8)34 (4.5)0.538
 Ischemic heart disease2103 (17.1)94 (12.5)0.015
ECGIschemic abnormalities389 (14.8)101 (13.4)0.451
hs-cTnIhs-cTnI, ng/L median (IQR)43.3 (3.6)3.2 (2.9)0.019
 hs-cTnI ≥5 ng/L, %187 (31.1)188 (24.9)0.011
Lung functionFEV1% of predicted value, mean (SD)75.8 (16.4)98.0 (10.8)< 0.001
 GOLD 1250 (41.6)n/a 
 GOLD 2307 (51.1)n/a 
 GOLD 3–444 (7.3)n/a 
  1. Presented as n (%) unless otherwise stated. Significant values in bold
  2. 1Hopsitalization due to respiratory condition
  3. 2Including angina pectoris, myocardial infarction, coronary artery bypass grafting (CABG) and/or percutaneous coronary intervention (PCI)
  4. 3Including Major Q/QS wave, major isolated ST-T abnormality, Minor Q wave plus major ST-T and minor isolated Q wave based on Minnesota coding
  5. 4Mann-Whitney U test, interquartile range (IQR)