Table 1 Basic characteristics of the study population, comparing individuals with COPD and normal lung function (NLF)
From: Cardiac biomarkers of prognostic importance in chronic obstructive pulmonary disease
Category | Variables | COPD (n = 601) | NLF (n = 755) | p |
|---|---|---|---|---|
Age | Age, mean (SD) | 67.0 (10.6) | 64.5 (11.3) | < 0.001 |
Sex | Women | 253 (42.1) | 361 (47.8) | 0.036 |
Smoking habits | < 0.001 | |||
Never smoker | 153 (25.5) | 354 (46.9) | ||
Ex-smoker | 250 (41.6) | 303 (40.1) | ||
Current smoker | 198 (32.9) | 98 (13.0) | ||
BMI groups | 0.025 | |||
BMI < 20 | 20 (3.3) | 12 (1.6) | ||
BMI 20–24.9 | 206 (34.3) | 238 (31.5) | ||
BMI 25–29.9 | 279 (46.4) | 347 (46.0) | ||
BMI ≥30 | 96 (16.0) | 158 (20.9) | ||
Oxygen saturation | Saturation percent, mean (SD) | 96.2 (2.2) | 97.1 (1.3) | < 0.001 |
Hypoxemia (< 92%) | 8 (1.3) | 0 (0) | 0.001 | |
Exacerbations | Hospital admission last 12 months1 | 11 (1.8) | 11 (1.5) | 0.589 |
Comorbidities | Diabetes mellitus | 54 (9.0) | 64 (8.5) | 0.742 |
Angina pectoris | 76 (12.2) | 80 (10.6) | 0.240 | |
Myocardial infarction | 35 (5.8) | 19 (2.5) | 0.002 | |
CABG and/or PCI | 23 (3.8) | 34 (4.5) | 0.538 | |
Ischemic heart disease2 | 103 (17.1) | 94 (12.5) | 0.015 | |
ECG | Ischemic abnormalities3 | 89 (14.8) | 101 (13.4) | 0.451 |
hs-cTnI | hs-cTnI, ng/L median (IQR)4 | 3.3 (3.6) | 3.2 (2.9) | 0.019 |
hs-cTnI ≥5 ng/L, % | 187 (31.1) | 188 (24.9) | 0.011 | |
Lung function | FEV1% of predicted value, mean (SD) | 75.8 (16.4) | 98.0 (10.8) | < 0.001 |
GOLD 1 | 250 (41.6) | n/a | ||
GOLD 2 | 307 (51.1) | n/a | ||
GOLD 3–4 | 44 (7.3) | n/a |