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Table 1 Baseline characteristics and laboratory tests of 349 patients

From: Dynamic changes of D-dimer and neutrophil-lymphocyte count ratio as prognostic biomarkers in COVID-19

 

Total (n = 349)

Survivors (n = 297)

Death (n = 52)

P

Gender (Male,%)

173(49.60%)

137(46.10%)

36(69.2%)

0.002

Age (years), n = 349

62.00(21.00–69.00)

60.00(50.00–67.00)

69.00(63.25–75.50)

< 0.001

Hospitalization days (days), n = 349

12.00(7.32–17.00)

11.00(7.00–16.00)

14.00(9.00–23.75)

0.006

Initial D-Dimer (mg/L), n = 349

0.39(0.17–0.95)

0.35(0.15–0.62)

1.81(0.52–9.34)

< 0.001

FIB(g/L),n = 345

3.83(3.13–4.79)

3.83(3.22–4.82)

3.92(2.89–4.71)

0.349

APTT(s),n = 347

34.80(32.40–38.50)

34.90(32.40–38.20)

34.60(32.08–41.48)

0.488

PT(s),n = 347

13.00(12.40–13.90)

12.80(12.40–13.50)

14.30(12.93–15.80)

< 0.001

Initial NLR, n = 349

3.33(1.94–9.42)

2.88(1.79–6.74)

14.96(8.52–26.58)

< 0.001

CRP (mg/L),n = 276

18.59(0.99–61.84)

12.31(0.84–47.08)

65.45(25.81–98.90)

< 0.001

PCT (ng/ml), n = 250

0.04(0.04–0.05)

0.04(0.04–0.04)

0.12(0.04–0.39)

< 0.001

TNI (ng/ml),n = 215

0.03(0.01–0.03)

0.01(0.01–0.03)

0.03(0.03–0.12)

< 0.001

NT-proBNP (pg/ml),n = 240

102.00(23.00–442.25)

64.00(16.50–249.00)

709.00(322.00–1282.00)

< 0.001

Comorbidity(n,%)

Respiratory failure

44(12.60%)

17(5.70%)

27(51.90%)

< 0.001

ARDS

35(10.00%)

11(3.70%)

24(46.20%)

< 0.001

Heart failure

16(4.60%)

5(1.70%)

11(21.20%)

< 0.001

AKI

14(4.00%)

1(0.30%)

13(25.00%)

< 0.001

Hypertension

103(29.50%)

73(24.60%)

30(57.70%)

< 0.001

Diabetes mellitus

57(16.30%)

41(13.80%)

16(30.80%)

0.004

Hypoproteinemia

71(20.30%)

53(17.80%)

18(34.60%)

0.009

  1. NOTE: Data are median (IQR), n (%). FIB fibrinogen; APTT activated partial thromboplastin time; PT prothrombin time; NLR neutrophil-to-lymphocyte ratio; CRP C-reactive protein; PCT procalcitonin; TNI troponin I; NT-proBNP N-terminal pro brain natriuretic peptide; ARDS acute respiratory distress syndrome; AKI acute kidney injury