Table 1 Baseline characteristics of 35 patients surgically treated for NTM-PD
Characteristics | No. (%) or median (IQR) |
|---|---|
Sex, female | 23 (65.7) |
Age, median (IQR) | 58 (47–65) |
Body mass index, mean (SEM) | 20.13 (17.93–21.36) |
Smoking status, never/former/current | 28 (80)/4 (11.4)/3 (8.6) |
Underlying disease/history | |
 Prior TB | 5 (14.3) |
 COPD | 1 (2.9) |
 Diabetes mellitus | 2 (5.7) |
 Lung resection | 2 (5.7) |
Species/group | |
Mycobacterium avium | 18 (51.4) |
M. intracellulare | 10 (28.6) |
M. kansasii | 1 (2.9) |
M. abscessus | 5 (14.3) |
 Undetermined | 1 (2.9) |
CAM-resistant strains | 8 (22.9) |
Chronic pulmonary aspergillosis | 3 (8.6) |
CT pattern | |
 Fibrocavitary | 17 (48.6) |
 Nodular bronchiectasis | 12 (34.3) |
 Unclassifiable | 3 (8.6) |
CT findings | |
 cavitation | 32 (91.4) |
 bronchiectasis | 25 (71.4) |
Pre- and postsurgical treatmenta | |
 No treatment | 3 (8.6) |
 On treatment | 32 (91.4) |
  CAM-included regimen ≥3 drugs | 29 (82.9) |
  CAM-included regimen with 2 drugs | 1 (2.9) |
  CAM monotherapy | 0 (0.0) |
  Non-CAM-included regimen | 2 (5.7) |
Treatment duration (months), median (IQR) | |
 Pre-surgical | 5.5 (2–34) |
 Post-surgical | 12 (3–20) |
Preoperative sputum examinations | |
 Positive AFB stain | 10 (28.6) |
 Positive AFB culture | 16 (45.7) |
Indications of surgery | |
 Poor response to medical therapy | 7 (20.0) |
 Remnant destroyed lesions | 23 (65.7) |
 Massive hemoptysis | 5 (14.3) |
Preoperative PFT, median (IQR) | |
 % FEV1, % | 87 (73.9–101.6) |
 % FVC, % | 95.4 (80.2–106.2) |
Postoperative PFT, median (IQR) | |
 % FEV1, % | 72.1 (61.63–95.25) |
 % FVC, % | 70.5 (56.25–92.15) |