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Table 3 Estimates of the association parameters for recurrent exacerbations and discontinuations using the joint frailty model

From: Improving the evaluation of COPD exacerbation treatment effects by accounting for early treatment discontinuations: a post-hoc analysis of randomized clinical trials

 

Frailty variance

Association (α)

Estimate (SE)*

Dataset A

1.84 (0.13)

0.99 (0.11)

Dataset B

0.87 (0.10)

1.84 (0.24)

Dataset C

2.17 (0.20)

1.28 (0.23)

Dataset D

1.34 (0.11)

0.93 (0.18)

Dataset E

0.74 (0.06)

0.83 (0.16)

  1. SE standard error, * - all parameters significantly different from zero with p-value < 0.0001