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Table 7 Adjusted odd ratios (ORs) and 95% confidence intervals (CIs) of interaction between OSA and sleep duration on insulin resistance

From: Interaction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study

predictors

n

OR (95% CI)

Model 1

Model 2

Model 3

Model 4

> 8 h*Primary snoring

72

0.633 (0.334–1.200)

0.735 (0.382–1.413)

0.622 (0.338–1.299)

0.670 (0.334–1.343)

> 8 h*OSA

466

1.094 (0.769–1.556)

1.034 (0.723–1.479)

0.931 (0.647–1.340)

0.860 (0.590–1.255)

7-8 h*Primary snoring

264

Reference

Reference

Reference

Reference

7-8 h*OSA

1493

1.338 (0.985–1.818)

1.272 (0.932–1.737)

1.176 (0.858–1.613)

1.070 (0.772–1.485)

6-7 h*Primary snoring

299

0.854 (0.577–1.264)

0.969 (0.650–1.445)

0.936 (0.623–1.405)

0.867 (0.569–1.322)

6-7 h*OSA

1411

1.215 (0.893–1.652)

1.190 (0.869–1.629)

1.099 (0.799–1.510)

1.046 (0.752–1.454)

5-6 h*Primary snoring

161

0.782 (0.489–1.250)

0.836 (0.517–1.350)

0.829 (0.510–1.347)

0.836 (0.509–1.371)

5–6*OSA

680

1.428 (1.027–1.987) *

1.442 (1.030–2.021) *

1.314 (0.933–1.850)

1.224 (0.858–1.744)

≤5 h*Primary snoring

144

0.628 (0.380–1.040)

0.647 (0.387–1.081)

0.638 (0.379–1.072)

0.604 (0.349–1.043)

≤5 h*OSA

457

1.622(1.143–2.303) *

1.615(1.127–2.315) *

1.467(1.018–2.116) *

1.384(0.949–2.020)

  1. Model 1 was adjusted for age, sex and BMI; model 2 was adjusted for variables included in model 1 and smoking, alcohol use, hypertension, hyperlipidemia, time in bed, S3, ESS; model 3 was adjusted for variables included in model 3 and waist hip ratio; model 4 was adjusted for variables in model 4 and additional diabetes mellitus, apolipoprotein A-1, apolipoprotein-B, apolipoprotein-E and lipoprotein-α
  2. Acronyms: OSA Obstructive sleep apnea, OR Odds ratio, CI Confidence interval, BMI Body mass index, ESS Epworth Sleepiness Scale, AHI Apnea-hypopnea index
  3. * p indicates a significant difference