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Table 4 Adjusted ORs and 95% CIs for the association of insulin resistance with OSA in stratified analysis by sleep duration

From: Interaction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study

Total sleep duration

n

OR (95% CI)

Model 1

Model 2

Model 3

Model 4

Model 5

> 8 h

 Primary snoring

72

Reference

Reference

Reference

Reference

Reference

  OSA

466

1.622 (0.867–3.034)

1.244 (0.639–2.422)

1.250 (0.640–2.440)

1.306 (0.657–2.593)

1.119 (0.545–2.298)

7-8 h

 Primary snoring

264

Reference

Reference

Reference

Reference

Reference

  OSA

1493

1.332 (0.968–1.833)

1.251 (0.903–1.734)

1.255 (0.905–1.740)

1.127 (0.806–1.575)

1.036 (0.732–1.468)

6-7 h

 Primary snoring

299

Reference

Reference

Reference

Reference

Reference

  OSA

1411

1.472 (1.076–2.014) *

1.287 (0.930–1.780)

1.286 (0.929–1.780)

1.244 (0.894–1.731)

1.287 (0.908–1.825)

5-6 h

 Primary snoring

161

Reference

Reference

Reference

Reference

Reference

  OSA

680

1.755 (1.128–2.731)*

1.643 (1.042–2.591) *

1.678 (1.062–2.649) *

1.559 (0.980–2.480)

1.454 (0.905–2.336)

≤5 h

 Primary snoring

144

Reference

Reference

Reference

Reference

Reference

  OSA

457

2.659 (1.628–4.344) *

2.500 (1.508–4.143) *

2.524 (1.524–4.180) *

2.196 (1.304–3.700) *

2.229 (1.283–3.874) *

  1. Model 1 was adjusted for age, sex and BMI; model 2 was adjusted for variables included in model 1 and smoking, alcohol use, hypertension, hyperlipidemia, time in bed, S3, ESS; model 3 was adjusted for variables included in model 2 and TST (or AHI); model 4 was adjusted for variables included in model 3 and waist hip ratio; model 5 was adjusted for variables in model 4 and additional diabetes mellitus, apolipoprotein A-1, apolipoprotein-B, apolipoprotein-E and lipoprotein-α
  2. Acronyms: OSA Obstructive sleep apnea, OR Odds ratio, CI Confidence interval, BMI Body mass index, TST Total sleep time, ESS Epworth Sleepiness Scale, AHI Apnea-hypopnea index
  3. * p indicates a significant difference
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Respiratory Research

ISSN: 1465-993X

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