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Table 2 Laboratory findings of patients with COVID-19 on admission

From: Predictors of fatality including radiographic findings in adults with COVID-19

 

Normal range

Total (n = 102)

Non-survivor (n = 15)

Survivor (n = 87)

p value

White blood cell count, × 109/L

4.00–10.00

6.0 (4.4–8.6)

9.1 (5.5–11.2)

5.8 (4.4–8.1)

0.011

< 4

 

11 (11%)

1 (7%)

10 (11%)

0.019

4–10

 

75 (74%)

8 (53%)

67 (78%)

..

> 10

 

16 (15%)

6 (40%)

10 (11%)

..

Neutrophil count, ×  109/L

1.80–6.30

4.2 (2.9–6.8)

8.0 (3.5–10.6)

4.1 (2.8–6.2)

0.006

Lymphocyte count, × 109/L

1.10–3.20

0.9 (0.6–1.2)

0.5 (0.4–0.8)

0.9 (0.7–1.2)

0.006

< 1·1

 

66 (65%)

12 (80%)

54 (62%)

0.180

≥1·1

 

36 (35%)

3 (20%)

33 (38%)

..

Hemoglobin, g/L

130.0–175.0

128.0 (115.0–138.0)

120.0 (110.0–135.0)

128.0 (115.0–139.0)

0.571

Platelet count, × 109/L

125.0–350.0

194.0 (152.0–250.5)

113.0 (97.0–165.0)

206.5 (162.8–267.5)

0.001

< 125

 

16/101 (16%)

9 (60%)

7/86 (8%)

0.000

≥125

 

85/101 (84%)

6 (40%)

79/86 (92%)

..

Lactate dehydrogenase, U/L

135–225

294.5 (219.3–417.5)

569.0 (362.0–664.0)

272.0 (205.0–383.0)

0.000

≤225

 

27 (26%)

1 (7%)

26 (30%)

0.060

> 225

 

75 (74%)

14 (93%)

61 (70%)

..

D-dimer, μg/mL

≤0·5

0.8 (0.5–1.7)

2.1 (1.2–4.4)

0.7 (0.4–1.5)

0.000

≤0·5

 

28 (27%)

1 (7%)

27 (31%)

0.002

> 0·5 to ≤1

 

29 (28%)

1 (7%)

28 (32%)

..

> 1

 

45 (45%)

13 (86%)

32 (37%)

..

Prothrombin time, s

11.5–14.5

14.2 (13.7–14.8)

14.9 (14.1–17.1)

14.1 (13.6–14.5)

0.001

< 14.5

 

65 (64%)

4 (27%)

61 (70%)

0.001

≥14.5

 

37 (36%)

11 (73%)

26 (30%)

..

International Normalized Ratio, INR

0.80–1.20

1.08 (1.04–1.15)

1.16 (1.08–1.37)

1.08 (1.02–1.12)

0.001

Hypersensitive troponin I, pg/mL

≤34.2

5.2 (2.2–16.2)

24.1 (13.0–202.1)

4.3 (2.0–10.6)

0.000

≤34.2

 

88/101 (87%)

8 (53%)

80/86 (93%)

0.000

> 34.2

 

13/101 (13%)

7 (47%)

6/86 (7%)

..

NT-proB-type Natriuretic Peptide (BNP), pg/mL

< 241

131.0 (53.5–355.8)

817.5 (348.5–3031.0)

92.5 (42.3–266.5)

0.000

< 241

 

64/100 (64%)

1/14 (7%)

63/86 (73%)

0.000

≥241

 

36/100 (36%)

13/14 (93%)

23/86 (27%)

..

Albumin, g/L

35–52

34.8 (31.7–39.5)

31.5 (28.5–34.0)

36.5 (32.5–39.8)

0.002

< 35

 

52 (51%)

13 (97%)

39 (45%)

0.003

≥35

 

50 (49%)

2 (13%)

48 (55%)

..

Alanine aminotransferase, U/L

≤41

23.0 (14.0–34.3)

17.0 (13.0–29.0)

23.0 (14.0–35.0)

0.223

≤41

 

86 (84%)

14 (93%)

72 (83%)

0.298

> 41

 

16 (16%)

1 (7%)

15 (17%)

..

Aspartate aminotransferase, U/L

≤40

26.0 (19.0–41.8)

34.0 (24.0–54.0)

25.0 (19.0–38.0)

0.187

≤40

 

75 (74%)

9 (80%)

66 (76%)

0.198

> 40

 

27 (26%)

6 (20%)

21 (24%)

..

Total bilirubin, μmol/L

≤26

8.5 (6.6–11.6)

8.4 (6.6–15.3)

8.5 (6.6–11.4)

0.752

Creatinine, μmol/L

59–104

68.0 (59.5–84.3)

94.0 (63.0–164.0)

67.0 (58.0–84.0)

0.014

≤104

 

89 (87%)

9 (60%)

80 (92%)

0.001

> 104

 

13 (13%)

6 (40%)

7 (8%)

..

Blood urea nitrogen, mmol/L

3.6–9.5

4.6 (3.2–6.2)

9.2 (5.4–13.7)

4.3 (3.2–5.5)

0.000

≤9.5

 

91 (89%)

8 (53%)

83 (96%)

0.000

> 9.5

 

11 (11%)

7 (47%)

4 (4%)

..

Potassium, mmol/L

3.50–5.10

4.2 (3.8–4.5)

4.4 (3.6–5.1)

4.1 (3.8–4.5)

0.171

< 3.5

 

13 (13%)

2 (13%)

11 (13%)

0.012

3.5–5.1

 

81 (79%)

9 (60%)

72 (83%)

..

> 5.1

 

8 (8%)

4 (27%)

4 (4%)

..

Sodium, mmol/L

136–145

137.7 (135.8–141.1)

138.6 (133.9–142.6)

137.6 (136.0–141.1)

0.970

< 136

 

26 (25%)

5 (33%)

21 (24%)

0.248

136–145

 

74 (73%)

9 (60%)

65 (75%)

..

> 145

 

2 (2%)

1 (7%)

1 (1%)

..

Calcium, mmol/L

2.20–2.55

2.1 (2.0–2.2)

2.0 (1.9–2.2)

2.1 (2.1–2.3)

0.004

< 2.2

 

70 (69%)

14 (93%)

56 (64%)

0.026

≥2.2

 

32 (31%)

1 (7%)

31 (36%)

..

Procalcitonin, ng/mL

< 0.05

0.06 (0.03–0.15)

0.19 (0.12–0.60)

0.05 (0.03–0.10)

0.000

< 0·05

 

40 (39%)

0 (0%)

40 (46%)

0.000

≥0·05

 

62 (61%)

15 (100%)

47 (54%)

..

High-sensitivity C-reactive Protein (hs-CRP), mg/L

< 1

34.0 (5.8–86.6)

78.7 (51.3–166.3)

25.4 (3.9–81.3)

0.003

< 3

 

16 (16%)

0 (0%)

16 (18%)

0.119

≥3

 

86 (84%)

15 (100%)

71 (82%)

..

IL-1β, pg/ml

< 5

4.9 (4.0–4.9)

4.5 (4.0–4.9)

4.9 (4.0–4.9)

0.388

IL-2R, U/ml

223–710

605.5 (380.8–896.8)

1166.5 (898.8–1788.5)

571.5 (353.0–821.8)

0.001

IL-6, pg/ml

< 7

4.7 (2.2–20.3)

48.4 (12.6–154.1)

4.2 (1.9–16.4)

0.000

IL-8, pg/ml

< 62

10.2 (6.7–19.9)

22.0 (14.0–28.4)

9.3 (6.4–18.6)

0.006

IL-10, pg/ml

< 9.1

4.9 (4.0–4.9)

4.9 (4.0–10.0)

4.9 (4.0–4.9)

0.601

TNF-α, pg/ml

< 8.1

7.5 (5.6–10.1)

13.0 (8.3–23.3)

7.3 (5.6–9.4)

0.006

  1. Data are median (IQR), n (%), or n/N (%), where N is the total number of patients with available data. p values comparing survivor with non-survivor were calculated by χ2 test, Fisher’s exact test, or Mann-Whitney U test, as appropriated. COVID-19, coronavirus disease 2019