Table 3 Predicting value for 5-year mortality in IPF patients assessed by Cox proportional hazards model
Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Serum (n = 79) | ||||||
 Age, years | 0.99 | 0.95–1.04 | 0.680 | – | – | – |
 Sex, Male/Female | 1.16 | 0.27–4.98 | 0.648 | – | – | – |
 Smoking history, pack-years | 1.00 | 0.98–1.01 | 0.825 | – | – | – |
 FVC, % predicted | 0.94 | 0.91–0.98 | < 0.001* | 0.94 | 0.91–0.98 | 0.002* |
 Serum esRAGE, ng/ml | 0.99 | 0.98–0.99 | 0.019* | 0.99 | 0.98–0.99 | 0.028* |
BALF (n = 57) | ||||||
 Age, years | 1.02 | 0.97–1.08 | 0.474 | – | – | – |
 Sex, Male/Female | 0.94 | 0.12–7.09 | 0.953 | – | – | – |
 Smoking history, pack-years | 0.99 | 0.97–1.01 | 0.330 | – | – | – |
 FVC, % predicted | 0.96 | 0.93–0.99 | 0.009* | 0.96 | 0.92–0.99 | 0.020* |
 BALF esRAGE, ng/ml | 0.99 | 0.99–0.99 | 0.009* | 0.99 | 0.98–0.99 | 0.041* |