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Table 1 Subject baseline characteristics

From: Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis

 

Controls

Patients with IPF

Serum

BALF

Subjects, n

90

79

57

Age, years

53.8 ± 3.6

67.4 ± 8.8*

66.5 ± 8.8*

Sex, Male/Female

77/13

70/9

53/4

Smoking history, pack-years

16.8 ± 18.3

39.4 ± 28.5*

38.3 ± 25.0*

FVC, % predicted

109.3 ± 16.2

78.7 ± 18.2*

78.7 ± 19.2*

DLco, % predicteda

–

50.2 ± 16.3

51.2 ± 16.1

BALF total cell, × 104/ml

–

–

21.9 ± 16.0

BALF macrophage, %

–

–

83.4 ± 11.4

BALF lymphocyte, %

–

–

11.4 ± 10.3

BALF neutrophil, %

–

–

3.3 ± 3.3

BALF eosinophil, %

–

–

1.9 ± 2.6

  1. *vs. Control, p < 0.05 Mann-Whitney U-test
  2. aDLco was measured in 73 of 79 IPF patients with serum sample and 55 of 57 patients with BALF sample, respectively
  3. Values are mean ± SD unless stated otherwise
  4. BALF bronchoalveolar lavage fluid, DLco diffusing capacity for carbon monoxide, IPF idiopathic pulmonary fibrosis, FVC forced vital capacity