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Table 1 Baseline characteristics of the study population

From: Compared to plasma, bronchial washing fluid shows higher diagnostic yields for detecting EGFR-TKI sensitizing mutations by ddPCR in lung cancer

 

Total (n = 73)

Early stage of lung cancer (n = 38)

Advanced stage of lung cancer (n = 35)

Age (year)

65.3 ± 9.8

65.0 ± 8.1

65.7 ± 11.5

Sex (F/M)

35/38 (47.9/52.1)

20/18 (52.6/47.4)

15/20 (42.9/57.1)

Smoking status

 Never smoker

45 (61.6)

25 (65.8)

20 (57.1)

 Former smoker

22 (30.1)

10 (26.3)

12 (34.3)

 Current smoker

6 (8.2)

3 (7.9)

3 (8.6)

Smoking amount (pack-year)

12.6 ± 21.4

11.3 ± 20.0

14.1 ± 23.2

Tumor type

 Adenocarcinoma

65 (89.0)

32 (84.2)

33 (94.3)

 Squamous cell carcinoma

7 (9.6)

5 (13.2)

2 (5.7)

 Sarcomatoid carcinoma

1 (1.4)

1 (2.6)

Tumor size (cm)

3.5 ± 2.0

3.0 ± 2.0

3.9 ± 1.9

Lung cancer stage

 I/II/III/IV

26/10/10/27

26/10/2/−

−/−/8/27

EGFR genotyping

 Wild type

35 (47.9)

18 (47.4)

17 (48.6)

 E19del

19 (26.0)

12 (31.6)

7 (20.0)

 L858R

19 (26.0)

8 (21.1)

11 (31.4)

  1. Note: Early stage refers to stage I - IIIA, and advanced stage refers to stage IIIB - IV
  2. Abbreviation: E19del, (c.2235del15; p.E746_A750del); L858R, (c.2573 T > G; p.Leu858Arg)