Local expression profiles of vitamin D-related genes in airways of COPD patients

Respiratory Research

Table 1 Patient characteristics (n = 10/group)

	Donor	COPD	p-value
Age	57 (55–69)	60.5 (54–62)	0.41
Gender (Male/Female)	7/3	7/3	> 0.99
Smoking history (Yes/No)	0/10^b	10/0	< 0.0001
Height (cm)	170 (167–180)	165 (159–174)	0.084
Weight (kg)	75 (65–90)	62 (53–74)	0.019
BMI (kg/m²)	25 (24–28)	23 (20–26)	0.057
FEV1%	NA	28,5 (23–36)	NA
FVC%	NA	73 (64–87)	NA
FEV1%/FVC%	NA	32 (27–37)	NA
DLCO%	NA	41 (35–54)^a	NA
TLC%	NA	123 (118–140)	NA
serum 25(OH)D (μg/L)	NA	26 (12–30)^a	NA
Vit D supplementation (Yes/No/NA)	0/0/10	8/2/0	NA

^aPretransplant 25(OH)D levels and DLCO% were unknown for 3 COPD patients. ^b Donors were registered as nonsmokers at the time of allocation Abbreviations: BMI: body mass index, FEV₁% % predicted forced expiratory volume in 1 s, FVC%: % predicted forced vital capacity, FEV1%/FVC: Tiffeneau index, DLco%: % predicted diffusion capacity, TLC%, % predicted total lung capacity. Values are Median with IQR. Depending on the normality of the data, either an unpaired t-test or a Mann-Whitney U test was used

ISSN: 1465-993X