Skip to main content
Fig. 2 | Respiratory Research

Fig. 2

From: Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway

Fig. 2

Effect of caffeine on the oxidative stress in lung and body weight of neonatal mice. After 14 days of high oxygen exposure, the SOD activity and GSH activity were decreased, and the MDA level was increased in the Hyperoxia (HO) group compared with the Normoxia (NO) group. Caffeine treatment reversed the hyperoxia-induced changes in these three oxidative indicators. a SOD activity in lung tissue. b MDA levels in lung tissue. c GSH activity in lung tissue. n = 6 mouse/group. d The body weight on postnatal day 7. (E) The body weight on postnatal day 14. n = 8 mice/group. *P < 0.05, **P < 0.01 HO group versus NO group, #P < 0.05, ##P < 0.01 Hyperoxia + Caffeine (HC) group versus HO group, ΨP < 0.05 NO group versus HC group

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us