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Fig. 1 | Respiratory Research

Fig. 1

From: Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway

Fig. 1

The concentration of caffeine in serum and expression of A2AR in lung. Caffeine treatment significantly increased the concentration of caffeine in serum and decreased the A2AR protein level in the lung. a The concentration of caffeine in serum as determined by ELISA. b The expression of A2AR in lung tissue as determined by IHC staining (light microscopy, × 200) and western blotting. Scale bars = 100 μm. The values are shown as the mean ± SD; n = 6 mouse/group. ▲▲P < 0.05 Normoxia (NO) group versus Normoxia +Caffeine (NC) group,ΨΨP < 0.01 NO group versus Hyperoxia + Caffeine (HC) group, **P < 0.01 HO group versus NO group, ##P < 0.01 HC group versus HO group., &&P < 0.01 HC group versus NC group

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