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Fig. 3 | Respiratory Research

Fig. 3

From: T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular vesicles

Fig. 3

T2 and T17 cytokines induce specific gene expression signatures in HBECs at air-liquid interface. a-b Next-generation sequencing was used to analyze RNA isolated from a single donor after 24 h stimulation. Top 20 upregulated genes after T2 (IL-4 + IL-13, a) and T17 (IL-17A + TNFα, b) stimulation. c Validation of a selection of upregulated genes by quantitative PCR (n = 5, each column represents expression in one donor). All data are expressed as log2 fold change compared to non-stimulated control

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