Number of participants, N (%) | ||||||
---|---|---|---|---|---|---|
Placebo (N = 102) | DNX 5 mg (N = 102) | DNX 10 mg (N = 103) | DNX 25 mg (N = 103) | DNX 35 mg (N = 102) | DNX 50 mg (N = 102) | |
Age (years) | ||||||
Mean (SD) | 66.2 (7.3) | 66.3 (6.8) | 65.7 (7.5) | 66.3 (7.3) | 65.1 (7.6) | 65.7 (7.0) |
Median | 67.0 | 66.5 | 66.0 | 67.0 | 65.0 | 66.0 |
Age group (years) | ||||||
18–64 | 43 (42) | 38 (37) | 45 (44) | 40 (39) | 46 (45) | 47 (46) |
65–74 | 46 (45) | 52 (51) | 47 (46) | 47 (46) | 45 (44) | 40 (39) |
75–84 | 13 (13) | 12 (12) | 11 (11) | 16 (16) | 11 (11) | 15 (15) |
Sex | ||||||
Female | 29 (28) | 36 (35) | 32 (31) | 38 (37) | 35 (34) | 32 (31) |
Male | 73 (72) | 66 (65) | 71 (69) | 65 (63) | 67 (66) | 70 (69) |
Ethnicity | ||||||
Hispanic/Latino | 1 (< 1) | 0 | 1 (< 1) | 3 (3) | 1 (< 1) | 3 (3) |
Not Hispanic/Latino | 101 (> 99) | 102 (100) | 102 (> 99) | 100 (97) | 101 (> 99) | 99 (97) |
Race | ||||||
Asian - East Asian Heritage | 10 (10) | 6 (6) | 18 (17) | 17 (17) | 10 (10) | 17 (17) |
Asian - South East Asian Heritage | 1 (< 1) | 0 | 0 | 0 | 0 | 0 |
Black or African American | 2 (2) | 2 (2) | 1 (< 1) | 0 | 0 | 1 (< 1) |
Native Hawaiian or other Pacific Islander | 1 (< 1) | 0 | 0 | 0 | 0 | 0 |
White - Arabic/North African Heritage | 1 (< 1) | 1 (< 1) | 0 | 0 | 0 | 0 |
White - White/Caucasian/European Heritage | 87 (85) | 93 (91) | 84 (82) | 86 (83) | 92 (90) | 84 (82) |