From: Predictive factors over time of health-related quality of life in COPD patients
SGRQ |  |  | β | SD(β) | P | OR | 95%CI |
---|---|---|---|---|---|---|---|
Impacts | Intercept |  | 3.150 | 0.229 | < 0.001 | – | – |
Time | (year) | −0.026 | 0.008 | 0.002 | 0.974 | (0.959–0.991) | |
Age | (5 years) | − 0.167 | 0.010 | < 0.001 | 0.846 | (0.829–0.864) | |
FEV1 | (100 ml) | −0.031 | 0.004 | < 0.001 | 0.970 | (0.962–0.978) | |
RV% | (9%) | 0.013 | 0.003 | < 0.001 | 1.013 | (1.007–1.019) | |
DLCO% | (11%) | −0.043 | 0.008 | < 0.001 | 0.958 | (0.943–0.973) | |
Handgrip | (5 kg) | −0.057 | 0.009 | < 0.001 | 0.945 | (0.928–0.962) | |
6mWT | (25 m) | − 0.053 | 0.005 | < 0.001 | 0.949 | (0.940–0.958) | |
Smoking | (10 pack/y) | 0.015 | 0.006 | 0.006 | 1.015 | (1.004–1.026) | |
BMI | ≤ 30 | – | – | – | – | – | |
>  30 | 0.129 | 0.032 | < 0.001 | 1.138 | (1.068–1.212) | ||
PA | < 2 h/week | – | – | – | – | – | |
2–4 h/week | −0.101 | 0.053 | 0.056 | 0.904 | (0.814–1.002) | ||
> 4 h/weeka | −0.256 | 0.052 | < 0.001 | 0.774 | (0.700–0.857) | ||
Work/intense | −0.433 | 0.061 | < 0.001 | 0.649 | (0.576–0.731) | ||
CCI | 0–3 | – | – | – | – | – | |
>  3 | −0.120 | 0.037 | 0.001 | 0.887 | (0.825–0.953) | ||
Treatmentb | 0–1 out of LABA/LAMA | – | – | – | – | – | |
2 out of LABA/LAMA/ICS | 0.141 | 0.058 | 0.014 | 1.152 | (1.028–1.290) | ||
LABA+LAMA+ICS | 0.087 | 0.050 | 0.084 | 1.090 | (0.988–1.203) | ||
Previous hospitalizations | 0 | – | – | – | – | – | |
1 | 0.043 | 0.041 | 0.294 | 1.044 | (0.964–1.131) | ||
2 | 0.257 | 0.060 | < 0.001 | 1.293 | (1.149–1.454) | ||
> 2 | 0.156 | 0.054 | 0.004 | 1.169 | (1.050–1.300) | ||
Sigmac |  | 0.951 | 0.030 | – | – | – |