Table 1 Sociodemographic and clinical characteristics of the cohort during the 5-years of follow-up
From: Predictive factors over time of health-related quality of life in COPD patients
Variable | Unit/Category | Baseline n = 543 | 1-year n = 480 (88%) | 2-years n = 428 (79%) | 5-year n = 324 (60%) |
|---|---|---|---|---|---|
SGRQ | Symptoms | 44.5 (22.2) | 42.5 (22.4) | 43.1 (23.5) | 44.1 (23.4) |
Activity | 48.7 (24.9) | 45.9 (25.0) | 46.6 (25.0) | 47.4 (25.4) | |
Impacts | 32.0 (20.9) | 30.4 (21.1) | 30.1 (20.4) | 30.4 (20.9) | |
Sex | M | 522 (96.1) | 459 (95.6) | 408 (95.3) | 308 (95.1) |
F | 21 (3.9) | 21 (4.4) | 20 (4.7) | 16 (4.9) | |
Age | Years | 68.3 (8.3) | 67.6 (8.4) | 67.4 (8.3) | 66.2 (8.4) |
BMI | Â | 28.3 (4.4) | 28.3 (5.2) | 28.1 (4.4) | 27.6 (4.8) |
Dyspnea (mMRC) | 0 | 69 (12.7) | 85 (17.7) | 75 (17.5) | 57 (17.6) |
1 | 264 (48.6) | 248 (51.7) | 188 (43.9) | 134 (41.4) | |
2 | 166 (30.6) | 127 (26.5) | 142 (33.2) | 100 (30.9) | |
3–4 | 44 (8.1) | 20 (4.3) | 23 (5.4) | 33 (10.2) | |
FEV1 | ml | 1465(441) | 1470(501) | 1513(470) | 1391(451) |
FEV1% | Percentage | 55.0 (13.3) | 55.2 (16.0) | 57.2 (14.7) | 54.3 (14.8) |
< 30 | 18 (3.3) | 22 (4.6) | 13 (3.0) | 14 (4.3) | |
30–50 | 167 (30.8) | 131 (27.3) | 111 (25.9) | 118 (36.4) | |
≥50 | 358 (65.9) | 327 (68.1) | 304 (71.0) | 192 (59.3) | |
RV% | Percentage | 159 (46.9) | 158 (47.7) | 158 (50.4) | 161 (48.4) |
DLCO% | Percentage | 71.5 (23.5) | 75.6 (26.6) | 76.7 (26.9) | 68.1 (21.9) |
Smoking habit/status | Pack/year | 46.8(27.3) | 46.3(26.4) | 46.5(26.0) | 46.8(25.9) |
Smoker | 114 (23.0) | 91 (19.0) | 79 (18.5) | 58 (17.9) | |
Former smoker | 414 (76.2) | 375 (78.1) | 338 (79.0) | 256 (79.0) | |
Non smoker | 15 (2.8) | 14 (2.9) | 11 (2.6) | 10 (3.1) | |
6mWT | Meters | 409 (92) | 421 (118) | 412 (116) | 397 (123) |
PA | < 2 h/week | 48 (8.8) | 44 (9.2) | 48 (11.2) | 62 (19.1) |
2–4 h/week | 110 (20.3) | 103 (21.5) | 94 (22.0) | 60 (18.5) | |
> 4 h/weeka | 219 (40.3) | 203 (42.3) | 165 (38.6) | 117 (36.1) | |
Work/intense | 166 (30.6) | 130 (27.1) | 121 (28.3) | 85 (26.2) | |
CCI | Points | 2.41(1.42) | 2.46(1.42) | 2.47(1.41) | 2.55(1.35) |
< 2 | 172 (31.7) | 145 (30.2) | 130 (30.4) | 87 (26.9) | |
2–3 | 264 (48.6) | 233 (48.5) | 208 (48.6) | 159 (48.8) | |
> 3 | 107 (19.7) | 102 (21.3) | 90 (21.0) | 79 (24.4) | |
Strength | Handgrip (kg) | 34.1 (9.4) | 33.7(10.2) | 33.0 (9.6) | 32.9(10.4) |
Previous hospitalizations | 0 | 427 (78.6) | 406 (84.6) | 377 (88.1) | 234 (72.2) |
1 | 80 (14.7) | 51 (10.6) | 30 (7.0) | 40 (12.4) | |
2 | 16 (3.0) | 14 (2.9) | 16 (3.7) | 23 (7.1) | |
3 | 9 (1.7) | 6 (1.3) | 4 (0.9) | 14 (4.3) | |
> 3 | 11 (2.0) | 3 (0.6) | 1 (0.2) | 13 (4.0) | |
Treatment b | 0–1 | 73 (13.4) | 57 (11.9) | 48 (11.2) | 36 (11.1) |
2 | 121 (22.2) | 91 (19.0) | 87 (20.3) | 56 (17.3) | |
3 | 349 (64.3) | 330 (68.8) | 293 (68.5) | 232 (71.6) |