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Table 1 Sociodemographic and clinical characteristics of the cohort during the 5-years of follow-up

From: Predictive factors over time of health-related quality of life in COPD patients

VariableUnit/CategoryBaseline
n = 543
1-year
n = 480 (88%)
2-years
n = 428 (79%)
5-year
n = 324 (60%)
SGRQSymptoms44.5 (22.2)42.5 (22.4)43.1 (23.5)44.1 (23.4)
Activity48.7 (24.9)45.9 (25.0)46.6 (25.0)47.4 (25.4)
Impacts32.0 (20.9)30.4 (21.1)30.1 (20.4)30.4 (20.9)
SexM522 (96.1)459 (95.6)408 (95.3)308 (95.1)
F21 (3.9)21 (4.4)20 (4.7)16 (4.9)
AgeYears68.3 (8.3)67.6 (8.4)67.4 (8.3)66.2 (8.4)
BMI 28.3 (4.4)28.3 (5.2)28.1 (4.4)27.6 (4.8)
Dyspnea (mMRC)069 (12.7)85 (17.7)75 (17.5)57 (17.6)
1264 (48.6)248 (51.7)188 (43.9)134 (41.4)
2166 (30.6)127 (26.5)142 (33.2)100 (30.9)
3–444 (8.1)20 (4.3)23 (5.4)33 (10.2)
FEV1ml1465(441)1470(501)1513(470)1391(451)
FEV1%Percentage55.0 (13.3)55.2 (16.0)57.2 (14.7)54.3 (14.8)
< 3018 (3.3)22 (4.6)13 (3.0)14 (4.3)
30–50167 (30.8)131 (27.3)111 (25.9)118 (36.4)
≥50358 (65.9)327 (68.1)304 (71.0)192 (59.3)
RV%Percentage159 (46.9)158 (47.7)158 (50.4)161 (48.4)
DLCO%Percentage71.5 (23.5)75.6 (26.6)76.7 (26.9)68.1 (21.9)
Smoking habit/statusPack/year46.8(27.3)46.3(26.4)46.5(26.0)46.8(25.9)
Smoker114 (23.0)91 (19.0)79 (18.5)58 (17.9)
Former smoker414 (76.2)375 (78.1)338 (79.0)256 (79.0)
Non smoker15 (2.8)14 (2.9)11 (2.6)10 (3.1)
6mWTMeters409 (92)421 (118)412 (116)397 (123)
PA< 2 h/week48 (8.8)44 (9.2)48 (11.2)62 (19.1)
2–4 h/week110 (20.3)103 (21.5)94 (22.0)60 (18.5)
> 4 h/weeka219 (40.3)203 (42.3)165 (38.6)117 (36.1)
Work/intense166 (30.6)130 (27.1)121 (28.3)85 (26.2)
CCIPoints2.41(1.42)2.46(1.42)2.47(1.41)2.55(1.35)
< 2172 (31.7)145 (30.2)130 (30.4)87 (26.9)
2–3264 (48.6)233 (48.5)208 (48.6)159 (48.8)
> 3107 (19.7)102 (21.3)90 (21.0)79 (24.4)
StrengthHandgrip (kg)34.1 (9.4)33.7(10.2)33.0 (9.6)32.9(10.4)
Previous hospitalizations0427 (78.6)406 (84.6)377 (88.1)234 (72.2)
180 (14.7)51 (10.6)30 (7.0)40 (12.4)
216 (3.0)14 (2.9)16 (3.7)23 (7.1)
39 (1.7)6 (1.3)4 (0.9)14 (4.3)
> 311 (2.0)3 (0.6)1 (0.2)13 (4.0)
Treatment b0–173 (13.4)57 (11.9)48 (11.2)36 (11.1)
2121 (22.2)91 (19.0)87 (20.3)56 (17.3)
3349 (64.3)330 (68.8)293 (68.5)232 (71.6)
  1. Frequencies and percentages by category for categorical variables, and mean and standard deviation for continuous variables are shown
  2. BMI body mass index, CCI Charlson comorbidity index, DLCO carbon monoxide diffusing capacity, Dyspnea mMRC Medical research council scale, FEV1 forced expiratory volume in the first second, PA physical activity, RV residual volume, 6mWT 6-min walking test
  3. a Gardening subjects were included in this category
  4. b Treatment has been classified as follows: 0–1 out of LABA/LAMA; 2 out of LABA/LAMA/ICS; 3 of them LABA+LAMA+ICS