Fig. 3

Effects of obesity on echocardiographic parameters in monocrotaline (MCT)-induced pulmonary hypertension (PH) in female Zucker rats. Echocardiography was performed after 5 weeks of either normal saline (NS) (lean NS (n = 10); obese NS (n = 10)) or monocrotaline (lean MCT (n = 10); obese MCT (n = 10)) treatment in lean and obese female Zucker rats. a Body mass index (BMI) of lean and obese female Zucker rats and (b-e) different echocardiographic parameters are given. RVID = right ventricular internal diameter, RVWT = right ventricular wall thickness, PAAT = pulmonary artery acceleration time, PAET = pulmonary artery ejection time, TAPSE = tricuspid annular plane systolic excursion. Data are presented as mean ± SEM (n = 10). p < 0.05 values are considered statistically significant. *compared to lean, ^$compared to normal saline