Characterisation of microbiota in saliva, bronchoalveolar lavage fluid, non-malignant, peritumoural and tumour tissue in non-small cell lung cancer patients: a cross-sectional clinical trial

Table 1 Characteristics of patients included in the study

	Total	Upper lobe T	Lower lobe T	p
No. of patients	18	10	8
Male/female	13/5	8/2	5/3
Age (years)	68 ± 8	65 ± 9	72 ± 6	0.061
BMI	25 ± 3	25 ± 4	25 ± 3	0.859
T in upper/middle/lower lobe	10/2/6	10/0/0	0/2/6
ADC/SCC/carcinoid	11/5/2	6/2/2	5/3/0
Stage I/II/III	8/2/8	5/2/3	3/0/5
Tumour size (cm)	3.7 ± 2.3	3.6 ± 2.4	3.9 ± 2.4	1
Smoker/ex-smoker/never-smoker	2/14/2	0/9/1	2/5/1
Pack-year (smokers, ex-smokers)	31 ± 20	31 ± 21	33 ± 20	0.823
FEV₁ (% of expected value)	98 ± 11	95 ± 8	101 ± 14	0.408
DLCO (% of expected value)	74 ± 16	81 ± 13	64 ± 16	0.034
FEV₁/FVC (% of expected value)	96 ± 10	95 ± 11	98 ± 10	0.630
Final no. of analysed samples
Saliva	17	10	7
BAL	15	8	7
LUNG.DP	17	10	7
LUNG.PT	14	9	5
LUNG.T	16	9	7

ADC adenocarcinoma, BAL bronchoalveolar lavage fluid, BMI body mass index, DLCO diffusing capacity of the lung for carbon monoxide, FEV₁ forced expiratory volume per second, FVC forced vital capacity, LUNG.DP non-malignant tissue, LUNG.PT peritumoural tissue, LUNG. T tumour, SCC squamous cell carcinoma, T tumour

ISSN: 1465-993X