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Fig. 3 | Respiratory Research

Fig. 3

From: Characterisation of microbiota in saliva, bronchoalveolar lavage fluid, non-malignant, peritumoural and tumour tissue in non-small cell lung cancer patients: a cross-sectional clinical trial

Fig. 3

Differential abundance between lung and salivary microbiota and their core composition. a Coloured nodes and branches in each tree represent the taxa with significantly different abundance between two compared microbiota. The colour intensity is proportional to log2-fold change in abundance in the favour of the sample with the same colour. Taxa names are shown in the common legend tree below comparisons. Statistical significance was assessed by zero-inflated general linear model using Wald’s test (DESeq2), with p-value threshold of α ≤ 0.05 after BH correction. b Core microbiota determined as OTUs present in 100% of each sample for one sample type. The colour represents relative abundance on transformed log4 scale. c Average value of sum of abundances of the core OTUs and of other OTUs per each subject in each sample types. BAL - bronchoalveolar lavage fluid, LUNG.DP - non-malignant distal piece, LUNG.PT - peritumoural tissue, LUNG. T – tumour, OTU – outer taxonomic unit

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