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Fig. 6 | Respiratory Research

Fig. 6

From: Suppressed nuclear factor-kappa B alleviates lipopolysaccharide-induced acute lung injury through downregulation of CXCR4 mediated by microRNA-194

Fig. 6

Mechanism of NF-κB on LPS-induced pulmonary inflammatory response via regulating the miR-194-mediated CXCR4. In LPS-induced ALI, NF-κB was activated to down-regulate the expression of miR-194. Consequently, miR-194 negatively regulated CXCR4 was up-regulated to release the inflammatory factors IL-1β, TNF-α and IL-6 which can promote inflammation response

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