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Fig. 5 | Respiratory Research

Fig. 5

From: High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

Fig. 5

Airway responsiveness to methacholine and percentages of specific airway resistance (sRaw) in the ovalbumin (OVA)-exposed group, titanium dioxide nanoparticle (TiO2 NPs)-exposed group, OVA plus TiO2 NP-exposed group, and controls upon methacholine stimulation (0, 12.5, 25, and 50 mg/mL) (Mice exposed to OVA showed an increase in sRaw, compared to the controls. Additional exposure to TiO2 NPs, along with OVA, resulted in an increase in sRaw. Data are presented as mean ± SEM, and n is presented in the graph for each condition)

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