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Fig. 3 | Respiratory Research

Fig. 3

From: High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

Fig. 3

Inflammatory cell count in bronchoalveolar lavage fluid (Total cells (a), macrophages (b), eosinophils (c), neutrophils (d), and lymphocytes (e) counts in bronchoalveolar lavage fluid obtained from different groups demonstrated an inflammatory response in the lungs after ovalbumin [OVA] exposure. Total cells, eosinophils, and lymphocytes counts were increased significantly in the OVA/OVA mice, compared to those in the phosphate buffered saline [PBS]/PBS controls [P < 0.05, P < 0.001, and P < 0.05, respectively]. Titanium dioxide nanoparticle treatment resulted in a significant increase in eosinophils count in the OVA/OVA mice [P < 0.05], indicating a greater asthmatic reaction response. Data are expressed as mean ± SEM for 5 to 10 mice per group. Inter-group comparison was performed using one-way ANOVA)

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