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Fig. 6 | Respiratory Research

Fig. 6

From: Targeted lung denervation in sheep: durability of denervation and long-term histologic effects on bronchial wall and peribronchial structures

Fig. 6

Pan-Neuronal Marker (pNM): (a) proximal, (b) activation site and (c) distal to the site of TLD therapy. (d) Semi-quantitative analysis of pNM staining in TLD treated nerves at 30 days (n = 6 animals, 11 airways), 365 days (n = 5 animals, 10 airways), and 640 days (n = 8 animals, 16 airways) at proximal to treatment site (open bars), treatment site (black bars), and distal to treatment site (diagonal stripe bars). At 30 days post TLD, a significant decrease in bronchial nerve expression of pNM demonstrates significant disruption of bronchial axons following TLD. Data are presented as mean ± SEM, *p < 0.001 vs proximal control

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Respiratory Research

ISSN: 1465-993X

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