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Fig. 7 | Respiratory Research

Fig. 7

From: SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation

Fig. 7

Nuclear translocation of p-p65 and p65 DNA binding activity. Each bar represents the mean ± SD. p-p65 level in nucleus was measured by western-blotting (A), and p65 DNA binding activity was determined by EILSA (B). Compared to control group, both expressions of p-p65 in nuclear and p65 DNA binding activity were significantly increased in LPS group. SN50 treatment decreased the p-p65 expression and weakened p65 DNA binding activity, indicating the inhibiting of translocation of p-p65 from cytoplasm to nuclear. ap<0.05 compared with Control. bp<0.05 compared with N-SN50. cp<0.05 compared with LPS. dp<0.05 compared with L-SN50

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Respiratory Research

ISSN: 1465-993X

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