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Table 3 Receive operating characteristics analysis. Predictors of lung transplant-free survival after the 2nd HRCT

From: Longitudinal functional changes with clinically significant radiographic progression in idiopathic pulmonary fibrosis: are we following the right parameters?

Variable

Area under the curve

Sensitivity

(C.I.)

Specificity

(C.I.)

p value

HRCT fibrosis score change (> 7%)

from baseline

0.61

52%

(38–66)

71%

(59–81)

0.0266

FVC change (≥5%)

from baseline

0.62

65%

(50–78)

60%

(47–71)

0.0193

TLC change (≥5%)

from baseline

0.56

55%

(39–70)

56%

(43–69)

n.s.

DLCO change (≥5%)

from baseline

0.57

70%

(53–84)

44%

(31–58)

n.s.