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Table 3 Receive operating characteristics analysis. Predictors of lung transplant-free survival after the 2nd HRCT

From: Longitudinal functional changes with clinically significant radiographic progression in idiopathic pulmonary fibrosis: are we following the right parameters?

Variable Area under the curve Sensitivity
(C.I.)
Specificity
(C.I.)
p value
HRCT fibrosis score change (> 7%)
from baseline
0.61 52%
(38–66)
71%
(59–81)
0.0266
FVC change (≥5%)
from baseline
0.62 65%
(50–78)
60%
(47–71)
0.0193
TLC change (≥5%)
from baseline
0.56 55%
(39–70)
56%
(43–69)
n.s.
DLCO change (≥5%)
from baseline
0.57 70%
(53–84)
44%
(31–58)
n.s.