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Table 2 Univariate regression analysis: predictors of lung transplant-free survival after the 2nd HRCT

From: Longitudinal functional changes with clinically significant radiographic progression in idiopathic pulmonary fibrosis: are we following the right parameters?

Variable Hazard ratio (C.I.) p value
Age (years) 1.01 (0.98–1.05) n.s.
Gender (male) 1.18 (0.65–2.24) n.s.
BMI (kg/m2) 0.96 (0.90–1.01) n.s.
Baseline HRCT fibrosis score 1.03 (1.01–1.06) 0.0057
HRCT fibrosis score change > 7% 2.10 (1.23–3.62) 0.0070
Baseline FVC 0.98 (0.97–0.99) 0.0126
FVC change ≥ 5% 2.13 (1.20–3.92) 0.0091
Baseline TLC 0.97 (0.95–0.99) 0.0081
TLC change ≥ 5% 0.99 (0.96–1.02) n.s.
Baseline DLCO 0.94 (0.94–0.98) < 0.0001
DLCO change ≥ 5% 1.31 (0.66–2.78) n.s.