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Table 1 Demographic, clinical and radiographic characteristics of the patients at baseline

From: Longitudinal functional changes with clinically significant radiographic progression in idiopathic pulmonary fibrosis: are we following the right parameters?

Variable

Average ± SD

Range

Age (years)

71 ± 8

43-89

Gender (% male)

72

 

BMI (kg/m2)

30 ± 5

 

Smoking (pack-years)

22 ± 20

0 - 113

MDD diagnosis

Clinical-radiographic-pathologic (%)

37 (30)

 

Clinical-radiographic (%)

86 (70)

 

FVC (% pred)

82 ± 21

38 - 132

TLC (% pred)

73 ± 16

40 - 118

DLCO (% pred)

50 ± 18

17 - 97

Antifibrotic therapy (%)

84 (68)

 

Pirfenidone (%)

39 (32)

 

Nintedanib (%)

23 (18)

 

Switched therapy (%)

22 (18)

 

Duration of antifibrotic therapy if any (months)

24 ± 23

1-82

Outcomes

Alive without LTx (%)

69 (56)

 

LTx (%)

11 (9)

 

Dead (%)

43 (35)

 

HRCT scan pattern

Definite UIP (%)

49 (40)

 

Probable UIP (%)

43 (35)

 

Indeterminate for UIP (%)

5 (4)

 

Alternative diagnosis (%)

26 (21)

 

Concomitant emphysema (%)

46 (37)

 
  1. Abbreviations: BMI body mass index, DLCO diffusion capacity, FVC forced vital capacity, HRCT high resolution CT scan, LTx lung transplant, MDD multi-disciplinary diagnosis, TLC total lung capacity, UIP usual interstitial pneumonia