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Table 1 Demographic, clinical and radiographic characteristics of the patients at baseline

From: Longitudinal functional changes with clinically significant radiographic progression in idiopathic pulmonary fibrosis: are we following the right parameters?

Variable Average ± SD Range
Age (years) 71 ± 8 43-89
Gender (% male) 72  
BMI (kg/m2) 30 ± 5  
Smoking (pack-years) 22 ± 20 0 - 113
MDD diagnosis
Clinical-radiographic-pathologic (%) 37 (30)  
Clinical-radiographic (%) 86 (70)  
FVC (% pred) 82 ± 21 38 - 132
TLC (% pred) 73 ± 16 40 - 118
DLCO (% pred) 50 ± 18 17 - 97
Antifibrotic therapy (%) 84 (68)  
Pirfenidone (%) 39 (32)  
Nintedanib (%) 23 (18)  
Switched therapy (%) 22 (18)  
Duration of antifibrotic therapy if any (months) 24 ± 23 1-82
Outcomes
Alive without LTx (%) 69 (56)  
LTx (%) 11 (9)  
Dead (%) 43 (35)  
HRCT scan pattern
Definite UIP (%) 49 (40)  
Probable UIP (%) 43 (35)  
Indeterminate for UIP (%) 5 (4)  
Alternative diagnosis (%) 26 (21)  
Concomitant emphysema (%) 46 (37)  
  1. Abbreviations: BMI body mass index, DLCO diffusion capacity, FVC forced vital capacity, HRCT high resolution CT scan, LTx lung transplant, MDD multi-disciplinary diagnosis, TLC total lung capacity, UIP usual interstitial pneumonia