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Fig. 1 | Respiratory Research

Fig. 1

From: IRF4 and STAT3 activities are associated with the imbalanced differentiation of T-cells in responses to inhalable particulate matters

Fig. 1

Peripheral blood mononuclear cell (PBMC) expression profiling in a healthy population reveals co-expressed gene modules in association with PM exposure. a, enrollment of healthy subjects from three cities in north China, Beijing, Taiyuan and Shijiazhuang; b, Three-week average exposure level (μg/m3) of PM2.5 (left) and PM10 (right) of each enrolled subject from the three cities; c, PBMC gene expression profile generated from the enrolled subjects; d, 18 co-expressed gene modules retrieved from the PBMC gene expression profiles with correlation coefficients to the exposure levels of five major pollutants shown heat colors and e, integrating DNA motif, transcription factor activity and KEGG pathway to infer transcription factors underlying the co-expressed gene modules (* P < 0.05, ** P < 0.01, *** P < 0.001)

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