Skip to main content
Fig. 8 | Respiratory Research

Fig. 8

From: Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways

Fig. 8

HO-1 inhibitor SnPP reversed the effects of ALT on CSE induced Beas-2B cells. a The commercially available ELISA kits were used to measure the level of TNF-α and IFN-γ; b Cell Death Detection PLUS ELISA assay was used to detect cell apoptosis; c DCFH-DA method was used to measure ROS production. Beas-2B cells were pre-treated with 5 μM ALT and SnPP (20 μM) for 2 h and then administrated with 5% CSE for 24 h. Data were expressed as mean ± S.D. from three independent experiments. *P values < 0.05 compared with the control group, #P values < 0.05 compared with the CSE group. CSE: cigarette smoke extract; ALT: Alantolactone

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us