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Fig. 4 | Respiratory Research

Fig. 4

From: Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways

Fig. 4

ALT inhibited CSE induced-LDH activity and apoptosis in Beas-2B a and NHBE b cells. LDH activity was measured using an LDH-cytotoxicity Kit; Cell Death Detection PLUS ELISA assay was used to detect cell apoptosis; Caspase-3 activity was measured by using Caspase-Glo 3/7 assay. Beas-2B and NHBE cells were pre-treated with 1, 5 and 10 μM ALT for 2 h and then administrated with 5% CSE for 24 h. Data were expressed as mean ± S.D. from three independent experiments. *P values < 0.05 compared with the control group, #P values < 0.05 compared with the CSE group. CSE: cigarette smoke extract; ALT: Alantolactone

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Respiratory Research

ISSN: 1465-993X

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