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Fig. 3 | Respiratory Research

Fig. 3

From: Inhibition of microRNA-451 is associated with increased expression of Macrophage Migration Inhibitory Factor and mitigation of the cardio-pulmonary phenotype in a murine model of Bronchopulmonary Dysplasia

Fig. 3

Inhibition of miR-451 is associated with increased neutrophils and protein in BAL fluid. a Total cell count values were obtained in RA and BPD mice, with and without treatment with a miR-451 inhibitor. Each bar represents the mean ± SEM of a minimum of 6 different animals. b BAL total neutrophil counts for WT RA and BPD mice, compared with those treated with a miR-451 inhibitor. Each bar represents the mean ± SEM of a minimum of 5 different animals. c BAL specimens from WT and miR-451 treated mice were evaluated for total protein content. Each bar represents the mean ± SEM obtained from a minimum of 7 different animals. BAL: bronchoalveolar lavage, RA: room air, BPD: bronchopulmonary dysplasia, WT: wild type, miR-451 Inh: miR-451 inhibitor treated. * p < 0.05, ** p < 0.01, ##p < 0.0001

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