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Fig. 1 | Respiratory Research

Fig. 1

From: Inhibition of microRNA-451 is associated with increased expression of Macrophage Migration Inhibitory Factor and mitigation of the cardio-pulmonary phenotype in a murine model of Bronchopulmonary Dysplasia

Fig. 1

Expression of miR-451 is upregulated by hyperoxia in MLECs and in murine lung tissues. a RNA was extracted from MLECs grown in room air and exposed to hyperoxia (95% O2) for 16 h. miR-451 expression was evaluated using RT-qPCR. N = 3, in each group. b RT-qPCR was performed on RNA extracted from the lungs of NB room air (RA) and BPD mice. N = 5, in each group. MLECs: mouse lung endothelial cells, RA: room air, Hyp – 16 h: hyperoxia for 16 h; NB: newborn; RA: room air; BPD: bronchopulmonary dysplasia. ** p < 0.01 # p < 0.001. Data are expressed as mean ± SEM

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Respiratory Research

ISSN: 1465-993X

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