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Table 3 Results of multivariate Cox proportional-hazards regression analyzing the effect of baseline variables on in-hospital death

From: Prognostic value of NT-proBNP in patients with severe COVID-19

Mode HR (95%CI) P
Not Adjusted NT-proBNP, per 100 pg/ml 1.369 (1.217–1.541) < 0.001
Mode 1
 NT-proBNP, per 100 pg/ml 1.323 (1.119–1.563) 0.001
 Female vs. Male 1.077 (0.330–3.518) 0.902
 Age, per 10 years 1.176 (0.719–1.922) 0.518
Mode 2
 NT-proBNP, per 100 pg/ml 1.342 (1.185–1.520) < 0.001
 HP, yes vs. no 1.613 (0.591–4.406) 0.351
 CHD, yes vs. no 1.219 (0.422–3.521) 0.714
Mode 3
 NT-proBNP, per 100 pg/ml 1.360 (1.177–1.572) < 0.001
 MYO, per 1 ng/ml 1.001 (0.996–1.005) 0.773
 CK-MB, per 1 μg/L 1.119 (0.905–1.385) 0.299
 Hs-TnI, per 0.1 ng/ml 1.031 (0.574–1.855) 0.918
Mode 4
 NT-proBNP, per 100 pg/ml 1.373 (1.188–1.586) < 0.001
 Urea, per 1 mmol/L 1.041 (0.936–1.158) 0.460
 Creatinine, per 1 umol/L 0.999 (0.974–1.025) 0.957
Mode 5
 NT-proBNP, per 100 pg/ml 1.248 (1.097–1.419) 0.001
 WBC, per 1 × 109/L 1.099 (1.015–1.190) 0.021
 LYM, per 1 × 109/L 0.163 (0.035–0.761) 0.021
Mode 6
 NT-proBNP, per 100 pg/ml 1.230 (1.003–1.509) 0.047
 WBC, per 1 × 109/L 1.036 (0.903–1.189) 0.611
 LYM, per 1 × 109/L 0.201 (0.033–1.221) 0.081
 CRP, per 1 mg/L 1.011 (0.999–1.023) 0.066
Mode 7
 NT-proBNP, per 100 pg/ml 1.200 (1.045–1.380) 0.010
 WBC, per 1 × 109/L 1.088 (0.016–1.164) 0.016
 LYM, per 1 × 109/L 0.151 (0.029–0.778) 0.024
 PCT, per 0.1 ng/ml 1.110 (1.010–1.220) 0.030
  1. Abbreviations: NT-proBNP N-terminal pro-brain natriuretic peptide, HP Hypertension, CHD Coronary heart disease, MYO Myoglobin, CK-MB Creatine kinase-MB, Hs-TnI High-sensitivity troponin-I, WBC White blood cell, LYM Lymphocytes, CRP C-reactive protein, PCT Procalcitonin, HR Hazards ratio; 95%CI 95% confidence interval
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