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Table 2 Results of univariate Cox proportional-hazards regression analyzing the effect of baseline variables on in-hospital death

From: Prognostic value of NT-proBNP in patients with severe COVID-19

Characteristics

HR (95%CI)

P

Sex

Male

 

Female

0.348 (0.130–0.930)

0.035

Age, per 10 years

1.975 (1.309–2.981)

0.001

History of HP

no

yes

4.044 (1.604–10.200)

0.003

History of CHD

no

yes

2.652 (0.992–7.092)

0.052

History of COPD

no

yes

4.127 (0.945–18.024)

0.059

History of DM

no

yes

0.958 (0.277–3.314)

0.947

NT-proBNP, per 100 pg/ml

1.369 (1.217–1.541)

< 0.001

MYO, per 1 ng/ml

1.006 (1.003–1.008)

< 0.001

CK-MB, per 1 μg/L

1.259 (1.098–1.443)

0.001

Hs-TnI, per 1 ng/ml

1.862 (1.273–2.722)

0.001

Urea, per 1 mmol/L

1.134 (1.073–1.198)

< 0.001

Creatinine, per 1 umol/L

1.028 (1.013–1.043)

< 0.001

WBC, per 1 × 109/L

1.150 (1.076–1.229)

< 0.001

LYM, per 1 × 109/L

0.065 (0.017–0.249)

< 0.001

CRP, per 1 mg/L

1.021 (1.012–1.030)

< 0.001

PCT, per 0.1 ng/ml

1.241 (1.142–1.349)

< 0.001

  1. Abbreviations: HP Hypertension, CHD Coronary heart disease, COPD Chronic obstructive pulmonary disease, DM Diabetes mellitus, NT-proBNP N-terminal pro-brain natriuretic peptide, MYO Myoglobin, CK-MB Creatine kinase-MB, Hs-TnI High-sensitivity troponin-I, WBC White blood cell, LYM Lymphocytes, CRP C-reactive protein, PCT Procalcitonin, HR hazards ratio, 95%CI 95% confidence interval