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Fig. 1 | Respiratory Research

Fig. 1

From: Letter to the editor: indacaterol/glycopyrronium/mometasone furoate compared with salmeterol/fluticasone propionate in patients with asthma: a randomized controlled cross-over study

Fig. 1

Effect of IND/GLY/MF (high- and medium-dose ICS) on peak FEV1 (L), standardized FEV1AUC5min–1h, FEV1AUC5min–23h45min, and trough FEV1 versus SFC (high-dose ICS) after 21 days of treatment. Peak FEV1 is defined as the highest bronchodilator effect on FEV1 during a period of 5 min to 4 h after the last evening dose of each treatment period. Standardized FEV1AUC is calculated as the area under the FEV1 curve over a specified time interval divided by the length of the time interval. Trough FEV1 is defined as the mean of FEV1 at 23 h 15 min and 23 h 45 min post-dose. CI: confidence interval; FEV1: forced expiratory volume in 1 s; GLY: glycopyrronium; ICS, inhaled corticosteroid; IND: indacaterol; MF: mometasone furoate; SFC, salmeterol/fluticasone combination

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