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Fig. 4 | Respiratory Research

Fig. 4

From: Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells

Fig. 4

Analysis of phosphorylated proteins in EV-treated lung epithelial cell. a Heat map of commonly phosphorylated protein found in A549 cells treated with 30 μg/ml of EVs vs. untreated. b Several proteins exhibited distinct phosphorylation variations in EV-treated and untreated cells. The volcano plot visualizes the p-values (adjusted for multiple testing) and corresponding log-fold changes. An adjusted p-value of 0.05 is indicated as horizontal line. Proteins with a positive log-fold change were more phosphorylated in EV-treated cells, and proteins with a negative log-fold change were more phosphorylated in untreated cells. c Individual array values of differentially phosphorylated proteins (TGM2, MMP-9, CADH1, and VACM) in A549 cells after EV treatment. Each sample was measured by four replicate spots per array

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