Covariate | Hazard Ratio | 95% Confidence Interval | p-value | |
---|---|---|---|---|
Age | 1.01 | 1.00 | 1.01 | 0.0011 |
Age Categories | ||||
  < 60 | Ref | Ref | Ref | Ref |
 [60, 70) | 2.02 | 1.67 | 2.43 | <.0001 |
 [70, 80) | 2.33 | 1.95 | 2.80 | <.0001 |
  ≥ 80 | 1.29 | 1.03 | 1.61 | 0.241 |
 Sex (Male) | 1.39 | 1.24 | 1.56 | <.0001 |
Health Authority | ||||
 Interior | 1.29 | 0.98 | 1.71 | 0.0744 |
 Fraser | 1.23 | 0.93 | 1.62 | 0.1485 |
 Vancouver Coastal | 1.04 | 0.78 | 1.40 | 0.7687 |
 Vancouver Island | 1.46 | 1.10 | 1.94 | 0.0084 |
 Northern | Ref | Ref | Ref | Ref |
Income Quintile | ||||
 5 | Ref | Ref | Ref | Ref |
 4 | 1.27 | 1.03 | 1.57 | 0.0246 |
 3 | 1.14 | 0.92 | 1.41 | 0.2152 |
 2 | 1.23 | 1.00 | 1.50 | 0.0491 |
 1 | 1.24 | 1.02 | 1.51 | 0.0305 |
Total Number of Prescriptions | 1.00 | 0.99 | 1.00 | <.0001 |
Charlson Comorbidity Score (Continuous) | 1.06 | 0.97 | 1.16 | 0.1853 |
Charlson Comorbidity Score (Categorical) | ||||
 0 | Ref | Ref | Ref | Ref |
 1 | 1.15 | 0.98 | 1.36 | 0.0931 |
 2 | 0.94 | 0.62 | 1.40 | 0.7459 |
  ≥ 3 | 0.90 | 0.55 | 1.48 | 0.6814 |
Inpatient Stay | 3.57 | 3.16 | 4.03 | <.0001 |
Number of hospitalizations | 1.66 | 1.64 | 1.68 | <.0001 |
COPD-related hospitalization | 2.56 | 2.00 | 3.27 | <.0001 |
CVD-related hospitalization | 1.04 | 0.58 | 1.88 | 0.8958 |
Combination Therapy (ICS/LABA) | 1.27 | 1.11 | 1.47 | 0.007 |
Number of physician encounters | 1.02 | 1.02 | 1.02 | <.0001 |
Oral glucocorticoid use | 1.09 | 0.91 | 1.30 | 0.3399 |