Table 1 Characteristics of subjects with available methylation data with their lung function of the IOW cohort
From: Changes of DNA methylation are associated with changes in lung function during adolescence
IOW cohort | ||||||
|---|---|---|---|---|---|---|
|  | Sub cohort at age 10: Participants with lung function Mean ± SD | Study sample at age 10: Participants with lung function and DNA-M Mean ± SD | P- values | Sub cohort at age 18: Participants with lung function Mean ± SD | Study sample at age 18: Participants with lung function and DNA-M Mean ± SD | P-values |
Factors | n = 980 | n = 320 |  | n = 838 | 453 |  |
Lung Function parameters | ||||||
FEV1(L) | 2.03 ± 0.30 | 2.04 ± 0.30 | 0.456 | 4.01 ± 0.78 | 4.05 ± 0.76 | 0.226 |
FVC (L) | 2.30 ± 0.34 | 2.30 ± 0.34 | 0.694 | 4.61 ± 0.93 | 4.66 ± 0.91 | 0.283 |
FEV1/FVC | 0.89 ± 0.06 | 0.89 ± 0.05 | 0.162 | 0.87 ± 0.07 | 0.87 ± 0.07 | 0.269 |
Height (cm) | 138.92 ± 6.18 | 138.06 ± 6.22 | 0.685 | 170.88 ± 9.17 | 170.92 ± 9.08 | 0.925 |
BMI | 18.16 ± 3.01 | 18.08 ± 2.99 | 0.649 | 23.21 ± 4.33 | 23.30 ± 4.26 | 0.639 |
| Â | n(%) | n(%) | Â | n(%) | n(%) | Â |
Gender | ||||||
Male | 488 (49.8) | 183 (57.19) | 0.010 | 395 (47.14) | 212 (46.80) | 0.932 |
Female | 492 (50.2) | 137 (42.81) | Â | 443 (52.86) | 241 (53.20) | Â |
Smokinga | ||||||
Non- smoker | – | – | – | 462 (55.13) | 248 (54.75) | 0.913 |
Current smoker | – | – |  | 204 (24.34) | 107 (23.62) |  |
Past smoker | – | – |  | 159 (18.97) | 93 (20.53) |  |
Missing | – | – |  | 13 (1.55) | 5 (1.10) |  |