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Table 1 Patient demographics and major clinical history

From: Microbial burden and viral exacerbations in a longitudinal multicenter COPD cohort

Age at Basine, years Patient characteristics*

Europea (n = 101)

USAb (n = 99)

P-value

Female

37 (36.7%)

33 (33.3%)

0.6

Age at Baseline, years

65 [50–81]

66 [51–93]

0.2

Smoking status

  

0.008

 Current

30 (29.7%)

26 (26.8%)

 

 Former

54 (53.5%)

67 (69%)

 

 Non-smoker

17 (16.8%)

4 (4.1%)

 

Smoking history, pack-years

31 [0–90]

51 [0–128]

1.0E-06

Years of COPD

9 [1–32]

11 [1–34]

0.02

Years of severe COPD

4 [1–15]

7 [1–33]

5.0E-04

GOLDcstage

  

0.9

 Mild

1 (0.9%)

0 (0%)

 

 Moderate

2 (2%)

2 (2%)

 

 Severe

69 (68.3%)

66 (68.8%)

 

 Very Severe

29 (28.7%)

28 (29.2%)

 

FEV1d

39 [17–85]

37 [13–71]

0.1

Frequent exacerbatore

18 (17.8%)

29 (29.3%)

0.06

Exacerbations per year

1.1 [0–11.8]

1.7 [0–12.1]

0.05

Congestive heart failure

28 (27.7%)

16 (16.2%)

0.06

Diabetes

25 (24.8%)

29 (29.9%)

0.4

Hypertension

61 (60.4%)

70 (72.1%)

0.08

Malignancy

2 (2%)

5 (5.1%)

0.2

  1. * Categorical data presented as number (proportion), and continuous variable as mean [range]
  2. a Patients recruited at 11 sites in Bulgaria and Czech Republic
  3. b Patients recruited at 14 sites in Alabama, Arizona, Georgia, Iowa, Nevada, New York, Ohio, Pennsylvania, Tennessee, Texas, Wisconsin
  4. c Global Initiative for Chronic Obstructive Lung Disease
  5. d Forced Expiratory Volume in 1 s, expressed in % of predicted based on height and weight
  6. e ≥ 2 exacerbations/ year